Description

n-Boc 5-Bromo-7-Methyl-1H-Indole-4-Carbaldehyde is a high-value, multi-functional indole derivative used as a critical synthetic intermediate in advanced organic chemistry. This compound matters because it provides a protected, reactive scaffold for constructing complex heterocyclic molecules, enabling precise molecular diversification. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, particularly in the synthesis of kinase inhibitors and other bioactive small molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for oncology and CNS targets.
• Kinase Inhibitor Development: Used to construct core indole structures in potential kinase inhibitor libraries.
• Agrochemical Research: Serves as a precursor for developing new active ingredients with specific biological activity.
• Material Science: A monomer or precursor for functional organic materials and advanced polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and custom synthesis projects for structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: The aldehyde functionality allows for condensation reactions to create novel peptidomimetics.

Basic Information

Product Name	n-Boc 5-Bromo-7-Methyl-1H-Indole-4-Carbaldehyde
CAS No.	1628640-26-5
Molecular Formula	C15H16BrNO3
Molecular Weight	338.20 g/mol
Synonyms	1H-Indole-4-carboxaldehyde, 5-bromo-7-methyl-, 1-(1,1-dimethylethyl) ester; tert-Butyl 5-bromo-7-methyl-4-formyl-1H-indole-1-carboxylate; 5-Bromo-7-methyl-1H-indole-4-carbaldehyde 1-Boc derivative; Boc-5-Bromo-7-methylindole-4-carboxaldehyde; 1-Boc-5-bromo-7-methyl-1H-indole-4-carbaldehyde; 5-Bromo-7-methyl-1-(tert-butoxycarbonyl)-1H-indole-4-carbaldehyde; N-Boc-5-bromo-7-methylindole-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our n-Boc 5-Bromo-7-Methyl-1H-Indole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.