Description

4-Chloro-5-Iodo-1H-Pyridin-2-One CAS NO 1628557-08-3 is a halogenated pyridinone derivative, a high-value heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a versatile precursor for constructing complex molecules through selective cross-coupling and functional group transformations. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions, including Suzuki and Sonogashira couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds.
• Chemical Biology Probes: Useful for creating molecular probes to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Chloro-5-Iodo-1H-Pyridin-2-One
CAS No.	1628557-08-3
Molecular Formula	C5H3ClINO
Molecular Weight	255.44 g/mol
Synonyms	4-Chloro-5-iodo-2-pyridone; 4-Chloro-5-iodo-1H-pyridin-2-one; 5-Iodo-4-chloro-2(1H)-pyridinone; 4-Chloro-5-iodopyridin-2(1H)-one; 2-Hydroxy-4-chloro-5-iodopyridine; 4-Chloro-5-iodo-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Iodo-1H-Pyridin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.