Description

1-[3-Chloro-4-(Dihydroxyboranyl)Phenyl]Cyclopropane-1-Carboxylic Acid is a sophisticated organoboron building block featuring a cyclopropane carboxylic acid moiety. This compound is of significant value in modern synthetic chemistry, particularly in cross-coupling reactions and as a key intermediate for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid/ester precursor for forming carbon-carbon bonds in medicinal chemistry.
• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized for creating labeled compounds and probes for biochemical assays and diagnostic research.
• Process Chemistry & Scale-up: A key intermediate for optimizing synthetic routes from laboratory to pilot and commercial scale.

Basic Information

Product Name	1-[3-Chloro-4-(Dihydroxyboranyl)Phenyl]Cyclopropane-1-Carboxylic Acid
CAS No.	1628507-88-9
Molecular Formula	C10H10BClO4
Molecular Weight	240.45 g/mol
Synonyms	[3-Chloro-4-(1-carboxycyclopropyl)phenyl]boronic acid; 1-[3-Chloro-4-boronophenyl]cyclopropane-1-carboxylic acid; (3-Chloro-4-(1-carboxycyclopropyl)phenyl)boronic acid; Cyclopropanecarboxylic acid, 1-[3-chloro-4-(dihydroxyboranyl)phenyl]-; Boronic acid, B-[3-chloro-4-(1-carboxycyclopropyl)phenyl]-; 3-Chloro-4-(1-carboxycycloprop-1-yl)benzeneboronic acid; CAS 1628507-88-9
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-4-(Dihydroxyboranyl)Phenyl]Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.