Description

2-(3-Chloro-2-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its value lies in enabling efficient, palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds containing biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific chlorinated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex organic molecules via Suzuki-Miyaura cross-coupling reactions.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, dyes, and pigments where precise molecular architecture is required.

Basic Information

Product Name	2-(3-Chloro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1628502-45-3
Molecular Formula	C13H18BClO3
Molecular Weight	268.54 g/mol
Synonyms	(3-Chloro-2-methoxyphenyl)boronic acid pinacol ester; 2-(3-Chloro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chloro-2-methoxybenzeneboronic acid pinacol ester; Pinacol (3-chloro-2-methoxyphenyl)boronate; (3-Chloro-2-methoxyphenyl)pinacolboronate; B-(3-Chloro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1628502-45-3
EINECS	Contact for details

Quality Control

Our 2-(3-Chloro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.