Description

Ethanone, 1-(2-Fluoro-3-Iodophenyl)- is a high-purity fluorinated and iodinated aromatic ketone building block, identified by CAS NO 1628003-72-4. This compound is valued for its unique halogenated structure, which provides versatile reactivity for constructing complex molecules in advanced chemical synthesis. It is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for use as a key intermediate in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	Ethanone, 1-(2-Fluoro-3-Iodophenyl)-
CAS No.	1628003-72-4
Molecular Formula	C8H6FIO
Molecular Weight	264.04 g/mol
Synonyms	1-(2-Fluoro-3-iodophenyl)ethanone; 2'-Fluoro-3'-iodoacetophenone; 2-Fluoro-3-iodoacetophenone; 1-Acetyl-2-fluoro-3-iodobenzene; 2-Fluoro-ω-iodoacetophenone; Acetophenone, 2'-fluoro-3'-iodo-; (2-Fluoro-3-iodophenyl)methyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(2-Fluoro-3-Iodophenyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.