Description

1-Methyl-1H-Indazol-3-Ylboronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional organic compounds. We supply this product with a focus on batch-to-batch consistency and reliable global availability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for constructing heterocyclic cores prevalent in medicinal chemistry.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products through palladium-catalyzed cross-coupling methodologies.
• Material Science Research: Serves as a precursor for synthesizing organic electronic materials, ligands for catalysis, and other functional organic molecules.
• Suzuki-Miyaura Cross-Coupling: The primary application, facilitating carbon-carbon bond formation between aryl/heteroaryl halides and this boronic ester under mild conditions.
• Chemical Library Development: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in discovery programs.
• Process Chemistry & Scale-Up: Employed in the optimization and commercial-scale production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Methyl-1H-Indazol-3-Ylboronic Acid Pinacol Ester
CAS No.	1627722-97-7
Molecular Formula	C₁₄H₁₉BN₂O₂
Molecular Weight	258.13 g/mol
Synonyms	1-Methyl-1H-indazol-3-ylboronic acid pinacol ester; (1-Methyl-1H-indazol-3-yl)boronic acid pinacol ester; 1-Methyl-1H-indazole-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-indazole; B-(1-Methyl-1H-indazol-3-yl)boronic acid pinacol ester; Pinacol 1-Methyl-1H-indazole-3-boronate; 1627722-97-7; 1-Methylindazole-3-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 1-Methyl-1H-Indazol-3-Ylboronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.