Description

2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline is a high-value, functionalized quinoline derivative containing a pinacol boronate ester group, making it a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable methods for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides, enhancing product efficacy and selectivity.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to the quinoline core's electron-transport properties.
• Ligand and Catalyst Development: Employed in the preparation of novel bidentate ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein function.

Basic Information

Product Name	2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline
CAS No.	1627721-83-8
Molecular Formula	C₁₆H₂₀BNO₂
Molecular Weight	269.15 g/mol
Synonyms	2-Methylquinolin-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylquinoline; 2-Methyl-4-(pinacolboron)quinoline; Quinoline, 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Methyl-4-quinolineboronic acid pinacol ester; 4-Borono-2-methylquinoline pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.