Description

7-Methoxy-1-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-C]Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry for constructing complex biaryl and heterobiaryl scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel small-molecule therapeutics, particularly in oncology and CNS disorders.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates targeting kinase inhibition.
• Medicinal Chemistry Research: Enables rapid structure-activity relationship (SAR) studies by providing a versatile handle for late-stage functionalization via palladium-catalyzed cross-coupling.
• Process Chemistry & Scale-Up: Serves as a critical raw material in the development of robust and scalable synthetic routes for clinical and commercial drug manufacturing.
• Chemical Biology Probes: Used in the creation of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of novel herbicides and fungicides containing complex heterocyclic structures.
• Material Science: Can be employed in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	7-Methoxy-1-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-C]Pyridine
CAS No.	1627713-58-9
Molecular Formula	C15H21BN2O3
Molecular Weight	288.15 g/mol
Synonyms	1-Methyl-7-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-methoxy-1-methyl-1H-pyrrolo[2,3-c]pyridine; 7-Methoxy-1-methyl-1H-pyrrolo[2,3-c]pyridine-3-boronic acid pinacol ester; 1H-Pyrrolo[2,3-c]pyridine, 7-methoxy-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1627713-58-9
EINECS	Contact for details

Quality Control

Our 7-Methoxy-1-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support development and commercial projects requiring consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.