Description

4-Benzyloxy-2-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboron reagent for forming carbon-carbon bonds in medicinal chemistry and material science.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing complex biaryl or heterobiaryl structures.
• Agrochemical Active Ingredient Development: Employed in creating new herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis.
• Organic Electronic Materials: A building block for π-conjugated polymers and small molecules used in OLEDs, OFETs, and solar cells.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic research.

Basic Information

Product Name	4-Benzyloxy-2-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1626407-70-2
Molecular Formula	C20H25BO4
Molecular Weight	340.22 g/mol
Synonyms	4-(Benzyloxy)-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-(phenylmethoxy)benzeneboronic acid pinacol ester; 4-Benzyloxy-2-methoxybenzeneboronic acid pinacol ester; (4-(Benzyloxy)-2-methoxyphenyl)boronic acid pinacol ester; 4-(Benzyloxy)-2-methoxybenzeneboronic acid, pinacol cyclic ester; B-[4-(Benzyloxy)-2-methoxyphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C, 11B), and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, supporting compliance with research and cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.