Description

Methyl4-(Bromomethyl)-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate CAS NO 1626407-50-8 is a high-value, multi-functional organic building block that combines a benzoate ester, a bromomethyl group, and a pinacol boronate ester in a single molecule. This compound is critical for facilitating advanced cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring boronic ester coupling for biaryl formation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate complex aromatic structures.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for methodology development and the construction of complex, polyfunctional aromatic compounds.
• Ligand & Catalyst Development: Used as a building block for synthesizing novel ligands and organometallic catalysts.

Basic Information

Product Name	Methyl4-(Bromomethyl)-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1626407-50-8
Molecular Formula	C15H20BBrO4
Molecular Weight	355.04 g/mol
Synonyms	Methyl 4-(Bromomethyl)-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 3-Boronic acid, 4-(bromomethyl)-, pinacol ester, methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(bromomethyl)benzoate; 4-(Bromomethyl)-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; 1626407-50-8; Methyl 4-bromomethyl-3-(pinacolatoboron)benzoate
EINECS	Contact for details

Quality Control

Our Methyl4-(Bromomethyl)-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.