Description

3-Amino-1H-Indazole-7-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its role in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis for creating complex molecular architectures. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those containing indazole and biaryl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors, where precise molecular design is critical.
• Cross-Coupling Reactions: Specifically designed as a boronic ester partner in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds.
• Chemical Biology & Proteomics: Can be employed in the synthesis of molecular probes and enzyme inhibitors for target identification and validation.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring new reaction methodologies.

Basic Information

Product Name	3-Amino-1H-Indazole-7-Boronic Acid Pinacol Ester
CAS No.	1626335-94-1
Molecular Formula	C₁₃H₁₈BN₃O₂
Molecular Weight	259.11 g/mol
Synonyms	7-Borono-1H-indazol-3-amine, 1,1-dimethylethyl ester; 3-Amino-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 1H-Indazole-7-boronic acid, 3-amino-, pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazol-3-amine; 3-Amino-7-(pinacolatoboryl)-1H-indazole; 3-Aminoindazole-7-boronic acid pinacol ester; 7-(Pinacolatoboryl)-1H-indazol-3-amine
EINECS	Contact for details

Quality Control

Our 3-Amino-1H-Indazole-7-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.