Description

2,4-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and materials science research. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and the creation of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, particularly those containing trifluoromethylpyridine and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific fluorinated aromatic structures.
• Material Science Precursor: Enables the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) with tailored electronic properties.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile bis-boronate reagent for the efficient construction of conjugated systems and complex polycyclic architectures.
• Chemical Research & Development: A valuable tool for medicinal chemists and synthetic organic chemists exploring new chemical space and reaction methodologies.

Basic Information

Product Name	2,4-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-6-(Trifluoromethyl)Pyridine
CAS No.	1622217-15-5
Molecular Formula	C20H28BF3NO4
Molecular Weight	413.06 g/mol
Synonyms	6-(Trifluoromethyl)pyridine-2,4-diylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); 2,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,4-Bis(pinacolatoboryl)-6-(trifluoromethyl)pyridine; 2,4-Bis(Bpin)-6-CF3-Pyridine; 6-CF3-2,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,4-Diboronic acid pinacol ester-6-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of our 2,4-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-6-(Trifluoromethyl)Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions and advanced R&D. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC/NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.