Description

2-Bromo-1-(3,4-Difluoro-2-Hydroxyphenyl)Ethan-1-One is a specialized fluorinated and brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both halogen and hydroxyl functional groups, makes it a versatile intermediate for constructing complex molecules with precise electronic and steric properties. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluorophenol moiety can enhance bioavailability and metabolic stability.
• Material Science Research: Serves as a building block for creating advanced polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-1-(3,4-Difluoro-2-Hydroxyphenyl)Ethan-1-One
CAS No.	1621375-69-6
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	2-Bromo-1-(3,4-difluoro-2-hydroxyphenyl)ethanone; 2-Bromo-3',4'-difluoro-2'-hydroxyacetophenone; 1-(3,4-Difluoro-2-hydroxyphenyl)-2-bromoethanone; α-Bromo-3,4-difluoro-2-hydroxyacetophenone; 2-Bromo-2'-hydroxy-3',4'-difluoroacetophenone; 1621375-69-6; Ethanone, 2-bromo-1-(3,4-difluoro-2-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(3,4-Difluoro-2-Hydroxyphenyl)Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.