Description

Xantphos Pd G4 is a highly active, fourth-generation palladium catalyst featuring the Xantphos ligand, designed for superior performance in demanding cross-coupling reactions. Its key value lies in providing enhanced stability, higher turnover numbers, and excellent selectivity, which are critical for efficient and cost-effective chemical synthesis. This advanced catalyst is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it enables the reliable construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key carbon-carbon and carbon-heteroatom bond formations (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling) for active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Facilitating the synthesis of complex, bioactive molecules used in crop protection agents and herbicides.
• Fine Chemical Production: Used in the synthesis of specialty chemicals, dyes, pigments, and advanced materials requiring precise catalytic control.
• Academic & Industrial R&D: A preferred catalyst for method development and exploring new synthetic pathways due to its robustness and versatility.
• Polymer Chemistry: Catalyzing polymerization reactions and the synthesis of functional monomers.
• Scale-up Process Chemistry: Ideal for transitioning from laboratory-scale discovery to pilot and commercial manufacturing, offering reliable performance under process conditions.

Basic Information

Product Name	Xantphos Pd G4
CAS No.	1621274-19-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Palladium Xantphos G4; Xantphos Palladacycle Gen. 4; Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); XPhos Pd G4 (related but distinct); Third-Generation Xantphos Precatalyst; Pd-PEPPSI-IPent (related class); Buchwald Palladacycle; Palladium Catalyst G4
EINECS	Contact for details

Quality Control

Our Xantphos Pd G4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high catalytic activity and purity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee consistency and performance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.