Description

Methyl 2,3-Difluoro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate CAS NO 1621256-23-2 is a high-purity, synthetically valuable boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the creation of fluorinated compounds which offer enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) for oncology, CNS, and anti-infective therapies.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the creation of advanced organic electronic materials, such as OLEDs and semiconductors, where fluorination tunes electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Enables the labeling and study of biological systems through incorporation into fluorinated molecular probes.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs engaged in custom synthesis projects for client-specific molecules.

Basic Information

Product Name	Methyl 2,3-Difluoro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1621256-23-2
Molecular Formula	C14H17BF2O4
Molecular Weight	298.10 g/mol
Synonyms	2,3-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 2,3-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2,3-Difluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)methyl benzoate; MFCD30566633; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-difluorobenzoic acid methyl ester; Benzoic acid, 2,3-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,3-Difluoro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.