Description

(3-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical reagent for forming carbon-carbon bonds in complex organic synthesis.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Potential precursor for creating functionalized organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.
• Process Chemistry & Scale-up: Employed in the route development and optimization for the commercial manufacturing of fine chemicals.

Basic Information

Item	Details
Product Name	(3-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Boronic Acid Pinacol Ester
CAS No.	1620575-05-4
Molecular Formula	C13H16BFN2O2
Molecular Weight	262.09 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; (3-Fluoro-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid pinacol ester; 3-Fluoro-1H-pyrrolo[2,3-b]pyridine-5-boronic acid pinacol ester; 1620575-05-4; 3-Fluoro-5-(pinacolatoboryl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our (3-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.