Description

2-Chloro-4-(Boc-Amino)Phenylboronic Acid, Pinacol Ester is a high-value, protected boronic acid ester building block essential for modern synthetic chemistry. Its core value lies in providing a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions while safeguarding the amine functionality, enabling the precise construction of complex molecular architectures. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Enables the creation of functionalized polymers, organic electronic materials, and liquid crystals through controlled coupling reactions.
• Chemical Biology & Proteomics: Serves as a valuable reagent for bioconjugation and the synthesis of molecular probes and inhibitors.
• Academic & Contract Research: A versatile tool for methodology development and complex molecule synthesis in research laboratories worldwide.

Basic Information

Product Name	2-Chloro-4-(Boc-Amino)Phenylboronic Acid, Pinacol Ester
CAS No.	1620228-06-9
Molecular Formula	C17H25BClNO4
Molecular Weight	353.65 g/mol
Synonyms	2-Chloro-4-((tert-Butoxycarbonyl)amino)phenylboronic acid pinacol ester; 4-(Boc-amino)-2-chlorophenylboronic acid pinacol ester; (2-Chloro-4-((tert-butoxycarbonyl)amino)phenyl)boronic acid pinacol ester; 2-Chloro-4-(N-Boc-amino)benzeneboronic acid pinacol ester; B-(2-Chloro-4-((tert-butoxycarbonyl)amino)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1620228-06-9; Boc-protected chlorophenylboronate
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Boc-Amino)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR (1H, 13C) for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to maintain stability and prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.