Description

Methyl 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a valuable boronic ester functional group. This compound is critical for enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex carbon-carbon bonds. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in constructing heterocyclic scaffolds common in active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of carbon-carbon bonds between aryl or heteroaryl groups, essential for creating complex molecular architectures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific pyrazole-boronate structures for optimal activity.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors, where precise molecular structure controls performance.
• Chemical Biology & Probe Development: Employed in creating molecular probes and labeled compounds for studying biological processes and target engagement.

Basic Information

Product Name	Methyl 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-3-Carboxylate
CAS No.	1616930-45-0
Molecular Formula	C12H19BN2O4
Molecular Weight	266.11 g/mol
Synonyms	1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylic acid methyl ester; Methyl 1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate; 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate; 1616930-45-0; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.