Description

1H-Indazole, 3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential boron-containing reagent for forming carbon-carbon bonds between aryl or heteroaryl groups under mild conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other advanced electronic components.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and labeled compounds for biochemical and diagnostic research.
• Academic & Contract Research: A valuable reagent for synthetic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	1H-Indazole, 3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1613639-49-8
Molecular Formula	C13H16BClN2O2
Molecular Weight	278.54 g/mol
Synonyms	3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 3-Chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 3-Chloro-1H-indazole-5-boronic acid pinacol ester; 5-(3-Chloro-1H-indazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1613639-49-8; 3-Chloro-5-(pinacolatoboryl)-1H-indazole; 3-Chloro-1H-indazole-5-boronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and traceability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.