Description

Cyclobutanecarboxylic Acid, 3-Fluoro-3-Methyl- is a high-value, fluorinated cyclobutane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom and a carboxylic acid group on a strained cyclobutane ring, makes it indispensable for modulating the physicochemical properties and metabolic stability of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom and cyclobutane scaffold can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials, where the fluorinated cyclobutane unit can impart unique thermal and chemical resistance properties.
• Chemical Biology & Probe Development: Utilized as a building block for fluorescent tags, molecular probes, and other tools in biochemical and diagnostic research.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Fluoro-3-Methyl-
CAS No.	1613330-60-1
Molecular Formula	C6H9FO2
Molecular Weight	132.13 g/mol
Synonyms	3-Fluoro-3-methylcyclobutanecarboxylic acid; 3-Fluoro-3-methyl-1-cyclobutanecarboxylic acid; 3-Methyl-3-fluorocyclobutanecarboxylic acid; (3-Fluoro-3-methylcyclobutyl)formic acid; Fluoromethyl cyclobutane carboxylic acid; 1613330-60-1; 3-Fluoro-3-methylcyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 3-Fluoro-3-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.