Description

2,3-Dichloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, multi-functional chemical building block that combines a phenol core with a boronic ester pinacol protecting group. This compound matters as a critical intermediate in modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting novel small molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific halogenated phenolic structures.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Essential reagent in academic and industrial labs for palladium-catalyzed cross-coupling reactions to create complex biaryl compounds.
• Ligand Synthesis: Precursor for creating sophisticated bidentate or polydentate ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,3-Dichloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	1612184-06-1
Molecular Formula	C12H15BCl2O3
Molecular Weight	289.96 g/mol
Synonyms	2,3-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 2,3-Dichloro-4-(pinacolboranyl)phenol; 4-Boronic acid, 2,3-dichlorophenol, pinacol ester; 2,3-Dichloro-4-pinacolatoboronphenol; 2,3-Dichloro-4-(pinacolatoboryl)phenol; 2,3-Dichloro-4-(pinacolboronate)phenol; Phenol, 2,3-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.