Description

2'-Fluoro-4-Hydroxy[1,1'-Biphenyl]-3-Carbaldehyde is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both aldehyde and phenolic hydroxyl groups on a fluorinated biphenyl scaffold, makes it a versatile building block for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials due to its rigid biphenyl structure.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific thermal, optical, or chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions and creating novel fluorinated aromatic compounds.
• Ligand & Catalyst Development: The aldehyde and hydroxyl functional groups make it a useful starting material for synthesizing chelating ligands and organocatalysts.

Basic Information

Item	Details
Product Name	2'-Fluoro-4-Hydroxy[1,1'-Biphenyl]-3-Carbaldehyde
CAS No.	1611443-83-4
Molecular Formula	C₁₃H₉FO₂
Molecular Weight	216.21 g/mol
Synonyms	2'-Fluoro-4-hydroxybiphenyl-3-carbaldehyde; 3-Formyl-2'-fluoro-4-hydroxy-1,1'-biphenyl; 4-Hydroxy-2'-fluorobiphenyl-3-carboxaldehyde; [1,1'-Biphenyl]-3-carboxaldehyde, 2'-fluoro-4-hydroxy-; 2'-Fluoro-4-hydroxy-3-biphenylcarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2'-Fluro-4-Hydroxy[1,1'-Biphenyl]-3-Carbaldehyde is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.