Description

2-[3-Bromo-5-(Trifluoromethoxy)Phenyl]-1,3-Dioxolane is a high-value, multi-functional aromatic building block featuring both bromo and trifluoromethoxy substituents. This compound is essential for research and development in advanced material science and pharmaceutical chemistry, offering unique reactivity for cross-coupling reactions and serving as a key precursor for complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Active Ingredient Synthesis: Serves as a key building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy group.
• Liquid Crystal & OLED Material Research: Used in the synthesis of advanced organic electronic materials due to its aromatic core and halogenated functional groups which influence electronic properties.
• Cross-Coupling Reactions (Suzuki, Buchwald-Hartwig): The bromine atom provides an excellent handle for palladium-catalyzed coupling reactions to construct complex biaryl systems.
• Polymer & Resin Modifier: Incorporated into polymer backbones to impart specific properties like flame retardancy or altered solubility.
• Chemical Biology & Probe Development: Utilized in creating fluorescent tags or molecular probes for biochemical assays and diagnostic applications.

Basic Information

Product Name	2-[3-Bromo-5-(Trifluoromethoxy)Phenyl]-1,3-Dioxolane
CAS No.	1610379-48-0
Molecular Formula	C10H8BrF3O3
Molecular Weight	313.07 g/mol
Synonyms	1,3-Dioxolane, 2-[3-bromo-5-(trifluoromethoxy)phenyl]-; 3-Bromo-5-(trifluoromethoxy)benzaldehyde ethylene acetal; 2-(3-Bromo-5-(trifluoromethoxy)phenyl)-1,3-dioxolane; [3-Bromo-5-(trifluoromethoxy)phenyl]-1,3-dioxolane; Benzaldehyde, 3-bromo-5-(trifluoromethoxy)-, cyclic ethylene acetal; 3-Bromo-5-trifluoromethoxybenzaldehyde ethylene acetal
EINECS	Contact for details

Quality Control

Every batch of 2-[3-Bromo-5-(Trifluoromethoxy)Phenyl]-1,3-Dioxolane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.