Description

3-Chloro-N,n-Dimethyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides that require specific chlorinated benzamide scaffolds for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Cross-Coupling Reactions: A dedicated Suzuki-Miyaura coupling partner for introducing the 3-chloro-4-boronobenzamide moiety into complex molecules under mild conditions.
• Chemical Biology & Proteomics: Utilized as a building block for creating chemical probes and affinity tags to study protein function and interactions.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing novel bidentate ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	3-Chloro-N,n-Dimethyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	1610372-97-8
Molecular Formula	C15H21BClNO3
Molecular Weight	309.59 g/mol
Synonyms	3-Chloro-N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-chloro-N,N-dimethylbenzamide; 3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzamide; Pinacol [3-Chloro-4-(dimethylcarbamoyl)phenyl]boronate; (3-Chloro-4-(dimethylcarbamoyl)phenyl)boronic acid pinacol ester; CAS 1610372-97-8; Benzamide, 3-chloro-N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-N,n-Dimethyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and scale-up activities, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.