Description

3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Cyclobutan-1-One CAS NO 1609119-82-5 is a high-value boronic ester derivative featuring a cyclobutanone moiety, serving as a critical advanced pharmaceutical intermediate (API) and organic synthesis building block. Its molecular architecture makes it indispensable for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential for forming carbon-carbon bonds between aryl/vinyl halides and boronic acids/esters under mild conditions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Materials Science Research: Precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Cyclobutan-1-One
CAS No.	1609119-82-5
Molecular Formula	C16H21BO3
Molecular Weight	272.15 g/mol
Synonyms	3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutan-1-one; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutan-3-one; 4-(3-Oxocyclobutyl)phenylboronic acid pinacol ester; (3-Oxocyclobutyl)phenyl-4-boronic acid pinacol ester; Pinacol [4-(3-oxocyclobutyl)phenyl]boronate; 3-(4-Boronophenyl)cyclobutanone pinacol ester; 1609119-82-5 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Cyclobutan-1-One adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.