Description

2,3-Dihydro-3Alpha-Methoxynimbolide is a high-purity, semi-synthetic derivative of nimbolide, a key limonoid compound with significant research interest. This modified analog is specifically engineered to enhance stability and bioavailability for advanced pharmaceutical and biochemical research applications. It is primarily utilized by research institutions and pharmaceutical development companies focusing on oncology, anti-inflammatory agents, and novel therapeutic pathways.

Application

• Pharmaceutical R&D: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anticancer and anti-inflammatory therapeutics.
• Biochemical Research: Used as a potent probe in molecular biology and cell biology studies to investigate mechanisms of apoptosis, NF-κB signaling inhibition, and other cellular pathways.
• Academic Research: Employed in universities and research institutes for pharmacological screening, structure-activity relationship (SAR) studies, and the synthesis of more complex nimbolide analogs.
• Standards and Metrology: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories requiring precise quantification of nimbolide-related compounds.

Basic Information

Product Name	2,3-Dihydro-3Alpha-Methoxynimbolide
CAS No.	1607828-35-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3α-Methoxy-2,3-dihydronimbolide; 2,3-Dihydro-3α-methoxynimbolide; 3-O-Methyl-2,3-dihydronimbolide; Nimbolide, 2,3-dihydro-3-methoxy-, (3α)-; Methoxydihydronimbolide; Dihydro-methoxynimbolide; Nimbolide derivative 1607828-35-2
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-3Alpha-Methoxynimbolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.