Description

2-(Difluoromethoxy)Cyclopentanamine is a specialized organofluorine building block featuring a cyclopentylamine core substituted with a difluoromethoxy group. This compound matters as a high-value intermediate for pharmaceutical and agrochemical research, enabling the introduction of fluorine atoms to modulate the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for synthesizing novel active ingredients and functional compounds.

Application

• Key synthetic intermediate in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Building block for agrochemicals, such as herbicides and fungicides, where the difluoromethoxy group can enhance efficacy.
• Precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Intermediate for the synthesis of fluorinated ligands and catalysts used in asymmetric synthesis.
• Starting material for advanced material science applications, including liquid crystals and specialty polymers.
• Reference standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2-(Difluoromethoxy)Cyclopentanamine
CAS No.	1603082-41-2
Molecular Formula	C6H11F2NO
Molecular Weight	151.16 g/mol
Synonyms	2-(Difluoromethoxy)cyclopentan-1-amine; Cyclopentanamine, 2-(difluoromethoxy)-; 1-Amino-2-(difluoromethoxy)cyclopentane; 2-(Difluoromethoxy)-1-cyclopentanamine; 2-(Difluoromethoxy)cyclopentylamine; 1-Cyclopentanamine, 2-(difluoromethoxy)-; 2-(Difluoromethoxy)cyclopentan-1-amine hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethoxy)Cyclopentanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, NMR, and MS confirmation. Our quality commitment supports cGMP development and scale-up processes for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend keeping the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain stability. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.