Description

2-Amino-3,4-Difluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an aldehyde and an amino group on a difluorinated benzene ring, makes it a critical precursor for constructing complex heterocyclic systems and functional materials. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms for enhanced bioactivity and material properties.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors, anticancer agents, and central nervous system (CNS) drugs where fluorine substitution is crucial.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to improve metabolic stability and membrane permeability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and dyes where the difluoroaniline moiety imparts specific electronic and optical properties.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.

Basic Information

Product Name	2-Amino-3,4-Difluorobenzaldehyde
CAS No.	1602097-79-9
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	3,4-Difluoro-2-aminobenzaldehyde; 2-Amino-3,4-difluorobenzenecarboxaldehyde; Benzenecarboxaldehyde, 2-amino-3,4-difluoro-; 3,4-Difluoroanthranilaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,4-Difluorobenzaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.