Description

2-[2-Chloro-6-(Methoxymethoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable synthetic pathways.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Precursor for organic electronic materials, including OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for diagnostic applications.
• Process Chemistry & Scale-up: Supports route development and optimization for commercial-scale manufacturing of fine chemicals.

Basic Information

Product Name	2-[2-Chloro-6-(Methoxymethoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1599432-42-4
Molecular Formula	C14H20BClO4
Molecular Weight	298.57 g/mol
Synonyms	2-(2-Chloro-6-(methoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol [2-Chloro-6-(methoxymethoxy)phenyl]boronate; (2-Chloro-6-(MOM)phenyl)boronic acid pinacol ester; 2-Chloro-6-(methoxymethoxy)benzeneboronic acid pinacol ester; Boronic acid, B-[2-chloro-6-(methoxymethoxy)phenyl]-, 1,1-dimethylethyl ester; MOM-Protected Chlorophenyl Boronic Ester
EINECS	Contact for details

Quality Control

Every batch of our 2-[2-Chloro-6-(Methoxymethoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of process chemistry and cGMP environments where applicable. Our quality management system is designed to support your regulatory filings. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.