Description

1-Cyclopropyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is primarily needed by pharmaceutical R&D and fine chemical synthesis laboratories for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing the dihydropyridone or pyridone core structures.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile organoboron reagent for forming carbon-carbon bonds with aryl or vinyl halides, a cornerstone reaction in medicinal chemistry.
• API Development: Used in research and process development for new Active Pharmaceutical Ingredients (APIs), especially in areas like kinase inhibitors and other targeted therapies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals, materials science, and specialty chemicals.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Item	Detail
Product Name	1-Cyclopropyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1596367-55-3
Molecular Formula	C14H20BNO3
Molecular Weight	261.13 g/mol
Synonyms	1-Cyclopropyl-6-oxo-1,6-dihydro-3-pyridineboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-cyclopropyl-2(1H)-pyridinone; 1-Cyclopropyl-6-oxo-1,6-dihydropyridine-3-boronic acid, pinacol ester; 1-Cyclopropyl-6-oxo-1,6-dihydro-3-pyridineboronic acid, pinacol ester; 3-Borono-1-cyclopropyl-6-oxo-1,6-dihydropyridine pinacol ester; (1-Cyclopropyl-6-oxo-1,6-dihydro-3-pyridinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.