Description

2-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, advanced pharmaceutical intermediate and organic building block featuring a protected boronic ester group. This compound is essential for modern synthetic chemistry, enabling precise carbon-carbon and carbon-heteroatom bond formation through cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to construct complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of drug candidates, particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science & OLED Development: Employed in the creation of organic electronic materials, including charge-transport layers and emissive materials for OLED displays.
• Chemical Biology & Probe Development: Facilitates the synthesis of labeled compounds and molecular probes for diagnostic and research applications.
• Scale-up & Process Chemistry: Supplied in quantities suitable for laboratory research through to pilot plant and commercial manufacturing scale.

Basic Information

Product Name	2-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1596338-61-2
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	2-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; 4-Amino-3-ethylphenylboronic acid pinacol ester; 2-Ethyl-4-(pinacolatoboryl)aniline; (4-Amino-3-ethylphenyl)boronic acid pinacol ester; 3-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethyl-aniline; B-(4-Amino-3-ethylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.