Description

2-(3-Bromonaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and materials science research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex polycyclic aromatic structures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex naphthalene-based scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific bromo- and boro-substituted aromatic systems.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating advanced organic semiconducting materials and charge transport layers in display and lighting technologies.
• Polymer Chemistry: Enables the synthesis of specialty polymers and conjugated materials with tailored electronic and optical properties.
• Ligand & Catalyst Development: Utilized as a starting material for constructing sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & Contract Research: A vital reagent for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	2-(3-Bromonaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1595078-11-7
Molecular Formula	C16H20BBrO2
Molecular Weight	335.05 g/mol
Synonyms	3-Bromo-2-naphthaleneboronic acid pinacol ester; (3-Bromonaphthalen-2-yl)boronic acid pinacol ester; 2-(3-Bromonaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; Pinacol (3-bromonaphthalen-2-yl)boronate; Naphthalene-2-boronic acid, 3-bromo-, 1,1-dimethylethyl ester; B-(3-Bromo-2-naphthyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(3-Bromonaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for advanced intermediates and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and light-sensitive nature. Keep away from heat, sparks, and open flame. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.