Description

1-Benzyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its stability and reactivity as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel synthesis for high-throughput screening in medicinal chemistry.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Benzyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1594127-49-7
Molecular Formula	C₁₈H₂₀BNO₃
Molecular Weight	309.17 g/mol
Synonyms	1-Benzyl-6-oxo-1,6-dihydropyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzylpyridin-2(1H)-one; 1-Benzyl-2-oxo-1,2-dihydropyridine-5-boronic acid pinacol ester; 1-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one; 1-Benzyl-6-oxo-1,6-dihydro-3-pyridineboronic acid pinacol ester; B-(1-Benzyl-6-oxo-1,6-dihydro-3-pyridinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Benzyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.