Description

3-(Difluoromethoxy)Cyclopentan-1-Amine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a difluoromethoxy group on a cyclopentane ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can influence biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the synthesis of fluorinated polymers or specialty chemicals where the cyclopentane-amine core contributes to specific material properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	3-(Difluoromethoxy)Cyclopentan-1-Amine
CAS No.	1592408-49-5
Molecular Formula	C6H11F2NO
Molecular Weight	151.16 g/mol
Synonyms	3-(Difluoromethoxy)cyclopentanamine; 1-Amino-3-(difluoromethoxy)cyclopentane; Cyclopentanamine, 3-(difluoromethoxy)-; 1592408-49-5; 3-Difluoromethoxycyclopentan-1-amine
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)Cyclopentan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.