Description

1,3,2-Dioxaborolane, 2-[2-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, sterically hindered organoboron reagent, specifically a pinacol boronic ester derivative. This compound matters as a critical synthetic intermediate, prized for its stability and reactivity in cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel aryl and heteroaryl frameworks.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl groups, essential in pharmaceutical and agrochemical synthesis.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex biaryl structures.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Process Chemistry & Scale-up: Suitable for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing due to its defined purity and handling characteristics.

Basic Information

Item	Details
Product Name	1,3,2-Dioxaborolane, 2-[2-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	1589507-60-7
Molecular Formula	C16H25BO2
Molecular Weight	260.18 g/mol
Synonyms	2-(2-tert-Butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(tert-Butyl)phenyl)boronic acid pinacol ester; 2-(2-tert-Butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-tert-Butylphenyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; tert-Butylphenylboronic acid pinacol ester; 2-(2-(tert-Butyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[2-(1,1-dimethylethyl)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[2-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All products undergo rigorous analytical testing, including NMR, HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.