Description

[1,2,4]Triazolo[1,5-A]Pyridine-6-Boronic Acid is a high-value boronic acid derivative and a key heterocyclic building block in modern synthetic chemistry. This compound matters for its crucial role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Academic & Contract Research: An essential reagent for methodology development and library synthesis in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	[1,2,4]Triazolo[1,5-A]Pyridine-6-Boronic Acid
CAS No.	1588769-34-9
Molecular Formula	C7H6BN3O2
Molecular Weight	174.95 g/mol
Synonyms	(1,2,4-Triazolo[1,5-a]pyridin-6-yl)boronic acid; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine (Pinacol ester precursor); 1,2,4-Triazolo[1,5-a]pyridine-6-boronic acid; 6-Borono-[1,2,4]triazolo[1,5-a]pyridine; TP-Boronic Acid; Triazolopyridine-6-boronic acid
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyridine-6-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.