Description

2-(2-Methoxyethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a versatile and highly valuable organoboron reagent, specifically a pinacol boronic ester derivative. This compound is a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the 2-methoxyethyl functional group into aromatic and heteroaromatic systems to create novel chemical entities.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing side chains that influence solubility and pharmacokinetics.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the methoxyethyl moiety can enhance biological activity.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules due to its reactivity and the properties of the incorporated ether group.
• Polymer Chemistry: Can be used as a monomer or functionalization agent to introduce boronate ester handles into polymer backbones for further modification.

Basic Information

Item	Details
Product Name	2-(2-Methoxyethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1581771-55-2
Molecular Formula	C9H19BO3
Molecular Weight	186.06 g/mol
Synonyms	2-(2-Methoxyethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Methoxyethyl)boronic acid pinacol ester; 2-Methoxyethylboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-(2-methoxyethyl)-4,4,5,5-tetramethyl-; Pinacol (2-methoxyethyl)boronate; 2-Methoxyethyl-Bpin
EINECS	Contact for details

Quality Control

Our 2-(2-Methoxyethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All products undergo rigorous analytical testing, including NMR, GC/HPLC, and Karl Fischer titration, to confirm identity, purity, and moisture content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.