Description

4,4,5,5-Tetramethyl-2-[2-(2-Propen-1-Yloxy)Phenyl]-1,3,2-Dioxaborolane is a specialized organoboron reagent featuring a vinyl-protected phenolic ether group. This compound matters as a versatile and reactive building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl and conjugated systems. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing key molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the boronate ester moiety into complex molecules.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Biology: Serves as a probe or linker in bioconjugation chemistry and the development of enzyme inhibitors.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[2-(2-Propen-1-Yloxy)Phenyl]-1,3,2-Dioxaborolane
CAS No.	1581724-10-8
Molecular Formula	C15H21BO3
Molecular Weight	260.14 g/mol
Synonyms	2-(2-(Allyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-Allyloxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(Allyloxy)phenylboronic acid pinacol ester; (2-(Allyloxy)phenyl)boronic acid pinacol ester; Allyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl ether
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[2-(2-Propen-1-Yloxy)Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; allow the sealed container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.