Description

2-[4-(3-Methoxypropoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced pharmaceutical intermediate belonging to the class of pinacol boronic esters. This compound, with CAS NO 1580442-17-6, serves as a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in pharmaceutical candidates.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of complex drug molecules, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the development of organic light-emitting diodes (OLEDs) and other functional organic materials.
• Chemical Research & Development: An essential tool for medicinal chemists and process chemists in lead optimization and route scouting.
• Scale-up and Commercial Manufacturing: Supplied in quantities suitable for pilot plant and commercial-scale API production under cGMP guidelines where required.

Basic Information

Product Name	2-[4-(3-Methoxypropoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1580442-17-6
Molecular Formula	C16H25BO4
Molecular Weight	292.18 g/mol
Synonyms	4-(3-Methoxypropoxy)phenylboronic acid pinacol ester; [4-(3-Methoxypropoxy)phenyl]boronic acid pinacol ester; Pinacol [4-(3-methoxypropoxy)phenyl]boronate; 2-[4-(3-Methoxypropoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(3-Methoxypropoxy)benzeneboronic acid pinacol ester; B-[4-(3-Methoxypropoxy)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-[4-(4-(3-Methoxypropoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material manufactured under cGMP conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.