Description

2-(4-((2-Methoxyethoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1580442-16-5 is a high-purity, functionalized phenylboronic ester derivative designed for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical manufacturing.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, widely used in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Liquid Crystal & OLED Material Development: Acts as a building block for creating organic electronic materials and advanced display components.
• Polymer & Resin Modification: Incorporated into polymer chains to introduce specific functional groups, altering material properties.
• Chemical Biology & Bioconjugation: Utilized in probe and linker synthesis for labeling and studying biological systems.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploratory chemistry in research laboratories.

Basic Information

Item	Detail
Product Name	2-(4-((2-Methoxyethoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1580442-16-5
Molecular Formula	C18H29BO5
Molecular Weight	336.23 g/mol
Synonyms	4-[(2-Methoxyethoxy)methyl]phenylboronic acid pinacol ester; [4-[(2-Methoxyethoxy)methyl]phenyl]boronic acid pinacol ester; 2-[4-[(2-Methoxyethoxy)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(2-Methoxyethoxymethyl)phenylboronic acid pinacol ester; (4-((2-Methoxyethoxy)methyl)phenyl)boronic acid pinacol ester; Pinacol 4-[(2-Methoxyethoxy)methyl]benzeneboronate; 1580442-16-5
EINECS	Contact for details

Quality Control

Our 2-(4-((2-Methoxyethoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and lot-to-lot consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.