Description

tert-Butyl n-Methyl-n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohex-3-En-1-Yl]Carbamate is a high-value, advanced pharmaceutical intermediate featuring a protected amine and a pinacol boronate ester functional group. This compound matters as a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction for constructing complex carbon-carbon bonds. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester moiety serves as a versatile handle for palladium-catalyzed coupling with aryl/heteroaryl halides.
• Medicinal Chemistry & Drug Discovery: Used in library synthesis and structure-activity relationship (SAR) studies to explore new chemical entities.
• Peptidomimetic Synthesis: The tert-butyloxycarbonyl (Boc) protected amine allows for the introduction of amino-cyclohexene scaffolds into peptide-like structures.
• Chemical Biology Probes: Employed in the development of molecular probes for target identification and validation in biological systems.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents.
• Material Science: Can be utilized in the synthesis of functional organic materials and ligands for catalysis.

Basic Information

Item	Detail
Product Name	tert-Butyl n-Methyl-n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohex-3-En-1-Yl]Carbamate
CAS No.	1572399-64-4
Molecular Formula	C18H32BNO4
Molecular Weight	337.27 g/mol
Synonyms	tert-Butyl N-methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl]carbamate; 4-(Boc-methylamino)cyclohex-3-ene-1-boronic acid pinacol ester; N-Boc-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-amine; 1-(tert-Butoxycarbonyl)-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexenylamine; 4-(N-Boc-N-methylamino)cyclohex-3-ene-1-boronic acid pinacol ester; Boc-N-methyl-4-(pinacolboronato)cyclohex-3-en-1-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-Methyl-n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohex-3-En-1-Yl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.