Description

1,7-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole CAS NO 1572397-96-6 is a high-value, functionalized indazole derivative featuring a pinacol boronate ester group. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile Suzuki-Miyaura cross-coupling building block for constructing complex molecules. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds for constructing complex biaryl and heterobiaryl structures in medicinal chemistry and material science.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, such as herbicides and fungicides.
• Ligand Synthesis: Serves as a building block for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: A potential monomer for constructing conjugated polymers and small molecules used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	1,7-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole
CAS No.	1572397-96-6
Molecular Formula	C₁₅H₂₁BN₂O₂
Molecular Weight	272.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,7-dimethyl-1H-indazole; 1,7-Dimethyl-1H-indazole-5-boronic acid pinacol ester; 1,7-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 1572397-96-6; 1H-Indazole, 1,7-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our production of 1,7-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.