Description

4,4,5,5-Tetramethyl-2-(4-Nitronaphthalen-1-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical synthetic intermediate. Its value lies in enabling precise and efficient cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Electronic Materials: Serves as a precursor for creating conjugated polymers and small molecules used in OLEDs, OFETs, and other optoelectronic devices.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new organic synthesis methodologies and complex molecule construction.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Polymer Chemistry: Acts as a functional monomer or end-capper in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(4-Nitronaphthalen-1-Yl)-1,3,2-Dioxaborolane
CAS No.	1565857-69-3
Molecular Formula	C₁₈H₂₂BNO₄
Molecular Weight	327.19 g/mol
Synonyms	1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-nitronaphthalene; 4-Nitronaphthalen-1-ylboronic Acid Pinacol Ester; (4-Nitronaphthalen-1-yl)boronic Acid Pinacol Ester; 4-Nitro-1-naphthaleneboronic Acid Pinacol Ester; 1-(4-Nitronaphthyl)boronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-(4-nitronaphthalen-1-yl)-1,3,2-dioxaborolane; PINACOL 4-NITRO-1-NAPHTHALENEBORONATE
EINECS	Contact for details

Quality Control

Every batch of 4,4,5,5-Tetramethyl-2-(4-Nitronaphthalen-1-Yl)-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. Our quality assurance protocols are designed to support cGMP and ISO standards for traceability and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.