Description

5-Nitro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value, synthetically versatile organoboron building block. This compound is critical for facilitating efficient cross-coupling reactions, enabling the rapid construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by enabling the introduction of the benzonitrile and nitro-substituted aryl motifs.
• Material Science: Serves as a building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: Employed in academic and industrial R&D for the preparation of complex, functionalized biaryl and heterobiaryl compounds.
• Ligand & Catalyst Development: Used as a substrate or precursor in the design and testing of new catalytic systems and ligands.

Basic Information

Product Name	5-Nitro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1565857-68-2
Molecular Formula	C₁₃H₁₅BN₂O₄
Molecular Weight	274.08 g/mol
Synonyms	2-(5-Nitro-2-cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2-Cyano-4-nitrobenzeneboronic acid pinacol ester; (5-Nitro-2-cyanophenyl)boronic acid pinacol ester; 1565857-68-2; 5-Nitro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; Boronic acid, B-(5-nitro-2-cyanophenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.