Description

(E)-Methyl 3-(3-Fluoro-4-Methylphenyl)Acrylate is a high-purity, fluorinated acrylate ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its specific substitution pattern introduces valuable fluorine and aromatic motifs. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Acts as a monomer or cross-linking agent to introduce specific aromatic and fluorinated properties into specialty polymers, enhancing thermal stability and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, such as cross-coupling reactions and cycloadditions, to create novel chemical entities.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on reaction kinetics, molecular conformation, and physicochemical properties.

Basic Information

Product Name	(E)-Methyl 3-(3-Fluoro-4-Methylphenyl)Acrylate
CAS No.	1563308-80-4
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	Methyl (E)-3-(3-Fluoro-4-methylphenyl)acrylate; Methyl 3-(3-Fluoro-p-tolyl)acrylate; (E)-3-(3-Fluoro-4-methylphenyl)-2-propenoic acid methyl ester; trans-Methyl 3-(3-fluoro-4-methylphenyl)acrylate; 2-Propenoic acid, 3-(3-fluoro-4-methylphenyl)-, methyl ester, (E)-; Methyl trans-3-(3-fluoro-4-methylcinnamate); 3-Fluoro-4-methylcinnamic acid methyl ester
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(3-Fluoro-4-Methylphenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring reproducible results and regulatory compliance in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.