Description

(E)-Methyl 3-Cyclobutylacrylate is a high-purity, unsaturated ester building block of significant interest in advanced organic synthesis. Its unique cyclobutyl-acrylate structure makes it a valuable precursor for constructing complex molecular frameworks with specific stereochemistry and functional properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Polymer & Material Science: Serves as a functional monomer for creating specialty polymers with tailored properties like adhesion, flexibility, or chemical resistance.
• Ligand & Catalyst Development: Employed in the preparation of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Flavor & Fragrance Chemistry: Acts as a building block for synthesizing complex ester-based aroma chemicals.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(E)-Methyl 3-Cyclobutylacrylate
CAS No.	1563295-95-3
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	Methyl (E)-3-Cyclobutylacrylate; (E)-Methyl 3-Cyclobutyl-2-propenoate; 3-Cyclobutylacrylic Acid Methyl Ester; trans-Methyl 3-Cyclobutylacrylate; Methyl trans-3-Cyclobutylacrylate; 2-Propenoic acid, 3-cyclobutyl-, methyl ester, (2E)-; Methyl (E)-3-cyclobutylprop-2-enoate
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-Cyclobutylacrylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, isomeric composition, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining under an inert atmosphere to preserve purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
(E)-Isomer Content (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.