Description

tert-Butyl4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohex-3-Enecarboxylate CAS NO 1562375-30-7 is a high-value, protected boronic ester derivative used as a key synthetic intermediate in advanced organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity building blocks for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing complex, functionalized carbon scaffolds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronate ester coupling partner for the formation of carbon-carbon bonds under mild conditions, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its structural features can be incorporated into bioactive molecules.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Advanced Material Precursor: Acts as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs or organic semiconductors.
• Chemical Biology Probes: Utilized to synthesize tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohex-3-Enecarboxylate
CAS No.	1562375-30-7
Molecular Formula	C₁₇H₂₉BO₄
Molecular Weight	308.22 g/mol
Synonyms	tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate; 3-Cyclohexene-1-carboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexenecarboxylic acid tert-butyl ester; tert-Butyl 4-(pinacolatoboryl)-3-cyclohexenecarboxylate; 4-(Pinacolatoboryl)-3-cyclohexenecarboxylic acid tert-butyl ester; tert-Butyl 4-(pinacol boronate)-3-cyclohexenecarboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohex-3-Enecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.