Description

Pyridine,4,4'-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3-Phenylene]Bis- is a specialized organoboron compound featuring a central phenylene core flanked by pyridine rings and a pinacol boronic ester functional group. This molecular architecture makes it a critical building block in advanced organic synthesis, particularly for constructing complex molecular frameworks. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, including pharmaceutical intermediates.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile precursor in the development of active pharmaceutical ingredients (APIs), especially those containing bipyridine or related heterocyclic structures.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands for transition metal catalysts in asymmetric synthesis and polymerization processes.
• Organic Electronic Materials: Employed in the research and production of organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its conjugated pyridine-phenylene system.
• Metal-Organic Framework (MOF) Construction: Functions as a functionalized linker molecule for creating porous coordination polymers with tailored properties for gas storage or catalysis.
• Agrochemical Research: Utilized as an intermediate in the discovery and synthesis of new crop protection agents and herbicides.

Basic Information

Item	Detail
Product Name	Pyridine,4,4'-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3-Phenylene]Bis-
CAS No.	1558024-18-2
Molecular Formula	C24H26B N2O2
Molecular Weight	376.29 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-phenylenebis(4-pyridine); 1,3-Bis(4-pyridyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1':3',1''-terphenyl]-4,4''-diyldipyridine; 4,4'-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-phenylene]dipyridine; Boronic acid, B-[3,5-bis(4-pyridinyl)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; Biphenyl-4,4'-diyldipyridine boronic ester pinacol
EINECS	Contact for details

Quality Control

Our high-purity organoboron intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including NMR (1H, 13C, 11B), HPLC, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.