Description

7,7-Difluoro-1-Methylbicyclo[4.1.0]Heptan-3-One is a specialized fluorinated bicyclic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a strained cyclopropane ring and strategically placed fluorine atoms, makes it a valuable precursor for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for synthesizing fluorinated polymers and advanced materials with unique surface properties.
• Catalysis & Ligand Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying cyclopropane ring-opening reactions and fluorine-specific transformations in academic and industrial R&D settings.

Basic Information

Product Name	7,7-Difluoro-1-Methylbicyclo[4.1.0]Heptan-3-One
CAS No.	1557247-48-9
Molecular Formula	C8H10F2O
Molecular Weight	160.16 g/mol
Synonyms	1-Methyl-7,7-difluorobicyclo[4.1.0]heptan-3-one; 7,7-Difluoro-1-methyl-3-oxabicyclo[4.1.0]heptane; Difluoromethylbicycloheptanone; 3-Keto-1-methyl-7,7-difluorobicyclo[4.1.0]heptane; 1557247-48-9; Bicyclo[4.1.0]heptan-3-one, 7,7-difluoro-1-methyl-
EINECS	Contact for details

Quality Control

Our 7,7-Difluoro-1-Methylbicyclo[4.1.0]Heptan-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material integrity for your sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.