Description

Taltirelin Acetate is a synthetic thyrotropin-releasing hormone (TRH) analog, specifically formulated as the acetate salt for enhanced stability and handling. This compound is of significant interest for its potent central nervous system activity and potential neuroprotective effects. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing treatments for neurological disorders and metabolic research.

Application

• Pharmaceutical Active Ingredient (API): Core component in the research and development of novel central nervous system (CNS) therapeutics.
• Neurological Research: Used in preclinical studies to investigate mechanisms related to ataxia, spinocerebellar degeneration, and other motor function disorders.
• Metabolic Pathway Studies: A key tool for studying the hypothalamic-pituitary-thyroid axis and its role in various physiological processes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratory settings.
• Peptide Chemistry Intermediate: Employed in further synthetic modifications to create novel peptide-based compounds for biological screening.

Basic Information

Product Name	Taltirelin Acetate
CAS No.	1549593-23-8
Molecular Formula	C17H25N7O4 • C2H4O2
Molecular Weight	463.47 g/mol (free base: 391.43 g/mol)
Synonyms	Taltirelin Acetate; Taltirelin Acetate Salt; TA-0910; (4S,5S)-5-Methyl-2-oxo-4-thiazolidinecarboxylic acid L-pyroglutamyl-L-histidyl-L-prolinamide acetate; CG-3703; TRH Analog TA-0910; L-Pyroglutamyl-L-histidyl-L-prolinamide, 5-oxo-1-prolyl-2-histidyl-N-[(4S,5S)-5-methyl-2-oxo-4-thiazolidinyl]-, acetate (1:1)
EINECS	Contact for details

Quality Control

Our Taltirelin Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.